Registration Dossier
Registration Dossier
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EC number: 204-468-9 | CAS number: 121-43-7
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- other information
- Study period:
- No data
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Meets generally accepted scientific standards with acceptable restrictions.
Data source
Reference
- Reference Type:
- publication
- Title:
- Occupational contact dermatitis from alkanolamine borates in metalworking fluids.
- Author:
- Bruze, M, Hradil, E, Erikson I-L, Gruvberger B and Widstrom
- Year:
- 1 995
- Bibliographic source:
- Contact Dermatitis 32: 24 - 27.
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- other: Three patients; no other data.
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: No data
- Deviations:
- not specified
- Principles of method if other than guideline:
- Three patients were patch tested. Case No 1: Al-test, Astra Agency, Sweden with 25 µL of test agent. Case 2 & 3 ; Finn Chamber, Epicon OY, Finland with 15 µL of test agent.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Borates
- IUPAC Name:
- Borates
- Details on test material:
- - Name of test material: Boric acid tested at 3 % w/v.
Constituent 1
Method
- Type of population:
- not specified
- Controls:
- No data
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- Not sensitising.
Applicant's summary and conclusion
- Conclusions:
- Boric acid tested at 3 % w/v in water showed no sensitisation in a patch test on three patients.
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