Registration Dossier
Registration Dossier
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EC number: 204-468-9 | CAS number: 121-43-7
Endpoint summary
Administrative data
Description of key information
Additional information
No terrestrial toxicity data are available for Trimethyl borate since the compound hydrolyzes in water with a half-life of less than 1 second to form methanol and boric acid. Methanol is much less toxic to environmental organisms compared to boric acid. Thus, PNEC values derived for boric acid are protective of the environment for the stoichiometric contribution of methanol .Therefore, terrestrial toxicity data compiled on boric acid was used. The endpoints included in the dossier under environmental hazard assessment were reported from studies on the ecotoxicity of boron and various compounds, such as boric acid (H3BO3), anhydrous sodium tetraborate (Na2B4O7), and hydrated sodium tetraborates (Na2B4O7. xH2O). All endpoints were converted to concentrations of elemental boron (B) using the relative molar mass and then converted to Trimethyl borate for this IUCLID. The geometric mean of the most sensitive endpoint of the most sensitive test species was used for the PNEC derivation. The most sensitive endpoint was juvenile production fromFolsomia candidawith a reported value of 15.5 mg B/kg resulting in an endpoint of 148.96 mg C3H9BO3/kg.
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