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Toxicity to aquatic algae and cyanobacteria

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Description of key information

No toxic effects up to the limit of water solubility (< 0.41 mg/L) for Scenedesmus subspicatus (OECD 201).

Key value for chemical safety assessment

Additional information

No studies investigating the toxicity of Glycerides, C16-18 and C18-unsatd. mono- (CAS No. 91744-09-1) to aquatic algae are available. Therefore, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to the structurally related category members Glycerides, C16-18 and C18-unsatd. (CAS No. 67701-30-8) was conducted. Further justification is given within the endpoint summary 6.1 and within the category justification section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance within this category was used.

One study evaluating the toxicity of Glycerides, C16-18 and C18-unsatd. to algae is available (Rieche, 1996). This limit test was conducted according to EU-Method C.3, under GLP conditions. The test was performed with additional consideration of the VCI concept for poorly soluble substances. Thus, two different test solutions were prepared with 100 mg/L: One solution where the test substance was directly weighed into the test vessel and undissolved substance was not removed and a second solution with separation of undissolved substance through filtration. No effect on the growth rate of Scenedesmus subspicatus was observed in the filtrated solutions and thus, it can be stated that no effect up to the limit of the water solubility of the test substances occurred under conditions tested. The effects observed in the oversaturated solutions with undissolved test substance can therefore be attributed to physical impacts of the undissolved test substances and not to a systemic toxicity of the tested substances.

Based on the results obtained for the structurally related analogue (in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5), Glycerides, C16-18 and C18-unsatd. mono- (CAS No. 91744-09-1) could exhibit low toxicity to algae.