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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

OECD Guideline 201, EU Method C3, GLP, key study, validity 1:

  • 72h-NOEC = 7.6 mg/L (growth rate)
  • 72h-ErC50 = 61 mg/L (growth rate)

Key value for chemical safety assessment

EC50 for freshwater algae:
61 mg/L
EC10 or NOEC for freshwater algae:
7.6 mg/L

Additional information

One valid key study is available to assess the toxicity of TBEP to aquatic algae. In this 72 -hour acute toxicity study, the cultures of Pseudokirchneriella subcapitata {61.81 SAG} were exposed to TBEP at nominal concentrations of 0.32, 1.0, 3.2, 10, 32 and 100 mg/L under static conditions in accordance with the OECD TG 201 and the EU Method C.3. The 72h-NOEC and 72h-EC50 values based on growth rate were 7.6 and 61 (95%IC: 59 -62) mg/L, respectively. The % growth inhibition in the treated algal culture as compared to the control ranged from 0.1% to 75% (over the period day 0 to day 3). At the end of the test, no abnormalities were noted on algal cells between algae growing in the medium at a nominal concentration of 32 mg/L and algae from the control group. There were no compound related phytotoxic effects.