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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1951
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: The study did not meet current guideline requirements for acute oral toxicity. It does however add weight of evidence for trichloro(phenyl)silane toxicity.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1951
Report Date:
1951

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Not enough information available to specify.
GLP compliance:
not specified
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
No data.

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
No data.
No. of animals per sex per dose:
No data.
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
2 400 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The LD50 value of 2.4 g/kg was determined in a study which did not meet current guideline requirements for acute oral toxicity. It does, however, add weight of evidence for trichloro(phenyl)silane toxicity.