Registration Dossier

Administrative data

Description of key information

There are no reliable acute toxicity data for trichloro(octyl)silane. However, in accordance with Column 2 of REACH Annexes VII and VIII, acute toxicity studies (required in Section 8.5) do not need to be conducted as the substance is classified as corrosive to skin.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

trichloro(octyl)silane hydrolyses very rapidly in contact with water and moist air releasing three moles of hydrogen chloride (HCl) for each mole of parent material. It is therefore classified as corrosive and acute toxicity testing is not appropriate.

Justification for classification or non-classification

Based on the available data, trichloro(octyl)silane does not require classification for acute toxicity according to Regulation (EC) No 1272/2008.