Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
skin irritation / corrosion, other
Remarks:
other: See "Principles of method if other than guideline"
Type of information:
other: epidemiological data from secondary source
Adequacy of study:
weight of evidence
Reliability:
other: No reliability score has been assigned

Data source

Reference
Reference Type:
secondary source
Title:
pp. 4030-4039
Author:
Rowe, V.K. and Wolf, M.A.
Year:
1982
Bibliographic source:
Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982.

Materials and methods

Principles of method if other than guideline:
No method is specified because the skin irritation/corrosion endpoint was assessed using a weight-of-evidence approach and a secondary source indicating that EGDN is unlikely to be a skin irritant.

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethylene dinitrate
EC Number:
211-063-0
EC Name:
Ethylene dinitrate
Cas Number:
628-96-6
Molecular formula:
C2H4N2O6
IUPAC Name:
ethane-1,2-diyl dinitrate

Results and discussion

In vivo

Results
Irritation parameter:
other:
Remarks:
not determined
Remarks on result:
not measured/tested

Applicant's summary and conclusion

Interpretation of results:
other: slightly irritating