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Diss Factsheets

Administrative data

Description of key information

LD50 (oral, rat) exceeds 2000 mg/kg bw
LD50 (dermal, rat) exceeds 2000 mg/kg bw
LC50 (rat, 4h) exceeded 2.75 +/- 0.19 mg/L, the maximum attainable concentration.

Key value for chemical safety assessment

Additional information

The key studies show very low acute oral toxicity via the 'normal' routes of exposure, viz. oral, dermal and inhalation. No mortalities occured in the key studies. The LD50/LC50s found in the key studies are supported by values from literature.

Via a non-physiological route of human exposure, viz intraperitoneal injection, the LD50 in mice was lower, viz. 160 mg/kg bw.

Justification for classification or non-classification

Key studies show that LD50 (oral, rat) exceeds 2000 mg/kg bw, LD50 (dermal, rat) exceeds 2000 mg/kg bw and LC50 (rat, 4h) exceeded 2.75 +/- 0.19 mg/L, the maximum attainable concentration.

Therefore classification for acute toxicity is not warranted.