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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15 JUN 2010 to 16 JUN 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187
Deviations:
not specified
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions) - Method B: Fibre Length and Diameter Distributions
Deviations:
not specified
GLP compliance:
yes
Type of method:
other: Optical microscope analysis and Laser diffraction particle size analysis
Type of distribution:
volumetric distribution
Percentile:
D50
Mean:
12.729 µm
St. dev.:
0.59

Full test results: All results are in μm.

 

Run 1

Run 2

Run 3

Run 4

Run 5

* Average

Volume weighted mean

19.301

20.109

19.865

19.231

19.183

19.538

Median (d.50)

12.651

12.839

12.802

12.675

12.686

12.729

Mode (μm)

13.299

13.012

13.108

13.214

13.299

13.189

10 % of material is <

2.781

2.782

2.786

2.787

2.802

2.788

50 % of material is <

12.651

12.839

21.802

12.675

12.686

12.729

90 % of material is <

45.622

47.888

47.008

45.151

45.009

46.122

* Average value was calculated from the entirety of data captured in each run and is not a simple arithmetic mean.

41.27 % by volume of the sample was seen to be < 10.00 μm.

Standard deviation results:

 

Run 1

Run 2

Run 3

Run 4

Run 5

Stdev

%STDV

d10

2.781

2.782

2.786

2.787

2.802

0.01

0.27

d50

12.351

12.839

12.802

12.675

12.686

0.08

0.59

d90

45.622

47.888

47.008

45.151

45.009

1.13

2.44

d15.78

58.110

57.380

57.540

58.070

58.060

0.31

0.53

GSD

0.218

0.224

0.222

0.218

0.218

0.00

1.13

Coefficient of variation for d50 was less than 3 %; d10 and d90 were less than 5 %. Thus repeatability of the characteristic particles in the size distribution were within the acceptable limits as per the BS ISO 13320 -1 test standard.

Conclusions:
In particle size distribution analysis 41.27 % by volume of the sample was seen to be < 10.00 μm. Coefficient of variation for d50 was less than 3 %; d10 and d90 were less than 5 %. Thus repeatability of the characteristic particles in the size distribution were within the acceptable limits as per the BS ISO 13320 -1 test standard.
Executive summary:

The particle size distribution of the test item was assessed in a guideline study (OECD 111, ISO 13320, CIPAC MT 187) according to GLP by laser diffraction method. The test item has a d50 of 12.729 µm, a d90 of 46.122 µm and a d10 of 2.788 µm.

Description of key information

The particle size distribution of the test item was assessed in a guideline study (OECD 111, ISO 13320, CIPAC MT 187) according to GLP by laser diffraction method. The test item has a d50 of 12.729 µm, a d90 of 46.122 µm and a d10 of 2.788 µm.

Additional information