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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

the short-term LC50 in fresh-water fish is 7 mg/l (over a period of 4 days). This single study was conducted according to OECD guidelines but without GLP. The mortality occurred exclusively above the solubility limit. A sharp dose-response curve was observed with 1/7 fish dead at 5.6 mg/l at the end of the test period and 7/7 dead fish at 10 mg/l already on the first day in test. The solubility is below 1 mg/l, based on precipitate observed.

Key value for chemical safety assessment

LC50 for freshwater fish:
7 mg/L

Additional information

TGMDA was tested on an acute toxicity assay for fresh water fish at concentrations of 0 - 10 mg/l over a period of 96 hours (4 -days)

At dose levels of 5.6 and higher TGMDA started to precipitate shortly after the beginning of the study, indicating that it was applied well above the solubility limit of the substance. Whether this had an influence on the LC50 is difficult to predict, however, it can be assumed that in the range of its solubility in water TGMDA is not toxic to fish.

The LC50 is therefore > the solubility limit of the substance.

It can be concluded that TGMDA is of moderate toxicity to fish, within its solubility limits of low toxicity.