Registration Dossier
Registration Dossier
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EC number: 239-898-6 | CAS number: 15793-73-4
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- other: case report
- Adequacy of study:
- supporting study
- Study period:
- 1985
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Case report
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 985
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 987
Materials and methods
- Study type:
- other: Case report
- Endpoint addressed:
- skin sensitisation
- Principles of method if other than guideline:
- no guideline required
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4,4'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-dihydro-5-methyl-2-(p-tolyl)-3H-pyrazol-3-one]
- EC Number:
- 239-898-6
- EC Name:
- 4,4'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-dihydro-5-methyl-2-(p-tolyl)-3H-pyrazol-3-one]
- Cas Number:
- 15793-73-4
- Molecular formula:
- C34H28Cl2N8O2
- IUPAC Name:
- 4,4'-[(3,3'-dichlorobiphenyl-4,4'-diyl)didiazene-2,1-diyl]bis[5-methyl-2-(4-methylphenyl)-2,4-dihydro-3H-pyrazol-3-one]
Constituent 1
Method
- Subjects:
- - Number of subjects exposed: 1
- Sex: female
- Age: 49
- Demographic information: cleaning personal
- Known diseases: sensitisation to rubber - Route of exposure:
- dermal
- Reason of exposure:
- intentional, occupational
- Exposure assessment:
- not specified
Results and discussion
- Clinical signs:
- symptoms: sharply defined glove dermatitis after wearing of PVC gloves
Any other information on results incl. tables
Patch test with glove: weak reaction
Other ingredients: negative
10 control tests with pigment (2% in petrolatum): negative
Applicant's summary and conclusion
- Executive summary:
One case report documents the sensitisation to Irgalite Orange F2G (Pigment Orange 34) after the use of PVC gloves.
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