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EC number: 231-718-4 | CAS number: 7699-45-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
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- Flash point
- Auto flammability
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- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
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- Nanomaterial Zeta potential
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- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
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- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to other aquatic organisms
Administrative data
- Endpoint:
- toxicity to other aquatic vertebrates
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable study which meets basic scientific principles
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- publication
- Title:
- Inhibition of carbon fixation as a function of zinc uptake in natural phytoplankton assemblages.
- Author:
- Davies AG & Sleep JA
- Year:
- 1 979
- Bibliographic source:
- J. mar. biol. Ass. U.K. 59: 937-949
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Photosynthetic inhibition (C fixation) test on phytoplancton communities in the field, designed for dose-response
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Zinc
- EC Number:
- 231-175-3
- EC Name:
- Zinc
- Cas Number:
- 7440-66-6
- IUPAC Name:
- zinc
- Details on test material:
- No information on salt used
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- The tests with zinc (plus 65Zn as a radioactive tracer) were carried out in natural sea water from Plymouth . The zinc background concentration in seawater was 0.4, 0.8 and 7.6 µg l-1 in the three samples
Test organisms
- Test organisms (species):
- other: multispecies test
- Details on test organisms:
- A series of three samples of varying biological composition were taken (100% diatoms - predominant species Rhizosolenia alata; 60% dinoflagellates/40% diatoms – predominant species Scrippsiella aff. trochoidea and R. stolterfothii; and 60% diatoms/40% dinoflagellates – predominant species as previous sample)
Study design
- Test type:
- static
- Water media type:
- saltwater
- Limit test:
- no
Test conditions
- Test temperature:
- 14°C
- Salinity:
- 35 ppt
- Nominal and measured concentrations:
- Nominal Zinc concentrations: 6 concentrations tested, 3 replicates / treatment
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 18 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 7 - <= 13 µg/L
- Nominal / measured:
- estimated
- Conc. based on:
- dissolved
- Basis for effect:
- other: C fixation rate
- Remarks on result:
- other: estimated from graph
- Duration:
- 18 h
- Dose descriptor:
- LOEC
- Effect conc.:
- >= 10 - <= 15 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- other: C fixation rate
- Details on results:
- The lowest concentrations of zinc which caused detectable inhibition of carbon fixation ( i.e. rates lower than 90% of the mean control values) were reported as being in the range of 10 to 15 µg l-1. From the dose-response curves presented in the paper, estimated EC10 levels were in the range of 7 to 13 µg l-1.
Test details: only fixation rates lower than 90% of the mean control value can be ascribed to zinc inhibition
Dose-response: yes
Control data: graphed - Reported statistics and error estimates:
- no statistics reported
Any other information on results incl. tables
no remark
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Relevant field study useful to check the protection level provided by the HC5 following from statistical extrapolation of single species tests data.
- Executive summary:
Davies and Sleep (1979) studied the effect of zinc on carbon fixation rates of natural phytoplankton communities present in the English channel. A series of three samples of varying biological composition were taken in July 1978, at approximately weekly intervals, at the same location. The tests with zinc (plus65Zn as a radioactive tracer) were carried out in natural sea water. The zinc background concentration in seawater was 0.4, 0.8 and 7.6 µg l-1in the three samples. The lowest concentrations of zinc which caused detectable inhibition of carbon fixation ( i.e. rates lower than 90% of the mean control values) were reported as being in the range of 10 to 15 µg l-1. From the dose-response curves presented in the paper, estimated EC10 levels were in the range of 7 to 13 µg l-1.
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