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Toxicological information

Repeated dose toxicity: oral

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Administrative data

Endpoint:
sub-chronic toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1989
Report date:
1989

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Limit test:
yes

Test material

Constituent 1
Test material form:
solid: particulate/powder

Test animals

Species:
rat
Strain:
Crj: CD(SD)
Sex:
male/female

Administration / exposure

Route of administration:
oral: feed

Results and discussion

Effect levels

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Dose descriptor:
NOAEL
Effect level:
7.85 mg/kg bw/day (nominal)
Based on:
test mat.
Sex:
male
Basis for effect level:
other:
Dose descriptor:
NOAEL
Effect level:
11.18 mg/kg bw/day (nominal)
Based on:
test mat.
Sex:
female
Basis for effect level:
other:

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion

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