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Administrative data

Endpoint:
repeated dose toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
other: Not applicable since exclusively summarizing data coming from a existing risk assessment (BUA Report) are presented as executive summary.

Data source

Reference
Reference Type:
other: Risk assessment
Title:
Phenylenediamines, BUA Report 97
Author:
GDCh-Advisory Committee on Existing Chemicals of Environmental Relevance (BUA)
Year:
1992
Bibliographic source:
edited by the GDCh-Advisory Committee on Existing Chemicals of Environmental Relevance, S. Hirzel, Wissenschaftliche Verlagsgesellschaft, Birkenwaldstraße 44, 70191 Stuttgart, 1995

Materials and methods

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion

Executive summary:

There are no recent and adequately documented studies on the toxicity after repeated administration. In the context of an inadequately documented carcinogenicity study in rat and mouse no striking mortality was described after dosages of 300 and approx. 2000 mg o-phenylenediamine x 2 HCl/kg bw.

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