Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-430-6 | CAS number: 95-54-5
Repeated dose toxicity: oral
Administrative data
- Endpoint:
- repeated dose toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- other: Not applicable since exclusively summarizing data coming from a existing risk assessment (BUA Report) are presented as executive summary.
Data source
Reference
- Reference Type:
- other: Risk assessment
- Title:
- Phenylenediamines, BUA Report 97
- Author:
- GDCh-Advisory Committee on Existing Chemicals of Environmental Relevance (BUA)
- Year:
- 1 992
- Bibliographic source:
- edited by the GDCh-Advisory Committee on Existing Chemicals of Environmental Relevance, S. Hirzel, Wissenschaftliche Verlagsgesellschaft, Birkenwaldstraße 44, 70191 Stuttgart, 1995
Materials and methods
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
- Executive summary:
There are no recent and adequately documented studies on the toxicity after repeated administration. In the context of an inadequately documented carcinogenicity study in rat and mouse no striking mortality was described after dosages of 300 and approx. 2000 mg o-phenylenediamine x 2 HCl/kg bw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
