Registration Dossier

Toxicological information

Specific investigations: other studies

Currently viewing:

Administrative data

Endpoint:
cytotoxicity
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable publication which meets basic scientific principles

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Toxicity of ethanol, n-butanol & iso-amyl alcohol in saccharomyces cerevisiae when supplied separately and in mixtures
Author:
Okolo B et al.
Year:
1981
Bibliographic source:
Biotechnology Letters 9, 431-434
Reference Type:
secondary source
Title:
No information
Author:
RIFM
Year:
2009
Bibliographic source:
RIFM database

Materials and methods

Test guideline
Qualifier:
no guideline available
GLP compliance:
no
Type of method:
in vitro
Endpoint addressed:
not applicable

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Iso-amyl alcohol

Test animals

Species:
other: Saccharomyces cerevisiae D
Strain:
not specified

Administration / exposure

Route of administration:
other: in medium
Vehicle:
unchanged (no vehicle)
Analytical verification of doses or concentrations:
no
Duration of treatment / exposure:
12 h
Frequency of treatment:
single application
Post exposure period:
no data
No. of animals per sex per dose:
not applicable

Results and discussion

Details on results:
LD20 = 1900 mg/kg
LD50 = 4300 mg/kg

Applicant's summary and conclusion