Registration Dossier
Registration Dossier
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EC number: 201-162-7 | CAS number: 78-96-6
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The substance is with high probability acutely not harmful to fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- > 215 - < 464 mg/L
Additional information
The results of a static exposure test conducted according to DIN 38412 part 15, using Leuciscus idus as test species (BASF AG, 1987), indicate that the test substance is with high probability acutely not harmful to fish. Based on nominal test item concentrations the 96h LC50 was determined to be in a range of 215 to 464 mg/L. Neutralization of the highest test concentration of 1000 mg/L completely abolished mortality. Therefore, the observed adverse effects may be related to pH.
The study was conducted without analytical monitoring. However, it is assumed that the test concentrations remained stable over the exposure period based on a high water solubility (miscible at any ratio; see IUCLID ch. 4.8), a low vapour pressure (0.63 hPa at 25 °C, see IUCLID ch. 4.6) a low Henry's Law constant (4.95E-05 Pa m³/mol, HENRYWIN v3.20, BASF SE, 2017) and a low adsorption potential (log Kow = -0.93, BASF AG, 1987; log Koc = 1.53, according to Franco&Trapp, BASF SE, 2021).
The findings of the key study were supported by results of a flow-through test with Pimephales promelas with a determined 96h LC50 of 2520 mg/L (Brooke, 1984). This study was conducted with analytical monitoring and a recovery rate of 96% of the test item was determined.
In conclusion, the substance is with high probability acutely not harmful to fish.
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