Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: OECD Guideline study

Data source

Reference
Title:
No information
Author:
Chemicals Evaluation and Research Institute (CERI), Japan|(1999a). Unpublished report
Year:
2002

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)

Test material

Constituent 1
Reference substance name:
Automatically generated during migration to IUCLID 6, no data available
IUPAC Name:
Automatically generated during migration to IUCLID 6, no data available
Details on test material:
IUCLID4 Test substance: other TS

TS-Freetext:
-Source: Wako Pure Chemical Industries,Ltd.
-Lot No.LEM4431
-Purity: 99.6 %

Results and discussion

Dissipation DT50 of parent compoundopen allclose all
pH:
4
Temp.:
25 °C
DT50:
34.9 h
pH:
7
Temp.:
25 °C
DT50:
33.1 h
pH:
9
Temp.:
25 °C
DT50:
36.4 h

Any other information on results incl. tables

RS-Freetext:
Half-life times of OCBC at 25 deg C:
=======================================================
pH    Half-life time        Temperature    Rate constant
      in hours (t1/2)        in deg C       in hours-1
-------------------------------------------------------
pH4   34.9              25             1.99E-2
pH7   33.1              25             2.1E-2
pH9   36.4              25             1.90E-2
=======================================================

RS-Freetext:
The o-chlorobenzyl chloride (OCBC) is hydrolyzed at pH 4.0,
7.0 and 9.0. (not stable in water)

Applicant's summary and conclusion