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EC number: 233-226-5 | CAS number: 10094-45-8
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to the analogue justification attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Parameter:
- % degradation (O2 consumption)
- Value:
- 8
- Sampling time:
- 28 d
- Remarks on result:
- other: Balk, 1989, Closed Bottle
- Parameter:
- % degradation (O2 consumption)
- Value:
- 23
- Sampling time:
- 28 d
- Remarks on result:
- other: Balk, 1989, RDA
- Parameter:
- % degradation (O2 consumption)
- Value:
- < 10
- Sampling time:
- 28 d
- Remarks on result:
- other: van Ginkel 1988;Closed Bottle
- Parameter:
- % degradation (O2 consumption)
- Value:
- 16
- Sampling time:
- 28 d
- Remarks on result:
- other: 0.15% SSA dipersion
- Remarks:
- Kolvenbach 1989; Closed Bottle
- Parameter:
- % degradation (O2 consumption)
- Value:
- 20
- Sampling time:
- 28 d
- Remarks on result:
- other: 0.020% SSA dispersion
- Remarks:
- Kolvenbach 1989, Closed Bottle
- Parameter:
- % degradation (O2 consumption)
- Value:
- 24
- Sampling time:
- 28 d
- Remarks on result:
- other: Maximum degree of degradation with non-adapted inoculum
- Remarks:
- Kolvenbach 1989, Sturm test
- Parameter:
- % degradation (O2 consumption)
- Value:
- 19
- Sampling time:
- 28 d
- Remarks on result:
- other: Maximum degree of degradation with non-adapted inoculum
- Remarks:
- Kolvenbach 1989, Sturm test
- Conclusions:
- Not readily biodegradable: < 10% - 24% degradation (OECD 301 D, 301 F, DGXI/400/84 EEC 19984, L251, 1984.09.19, Part C, EEC 1984)
- Executive summary:
Studies on the ready biodegradability of (Z)-N-octadecyldocos-13-enamide (CAS No. 10094-45-8) are not available. Therefore data of the analogue substance N-octadecylstearamide (stearyl stearamide, CAS 13276 -08 -9) were used as read-across. The ready biodegradability of N-octadecylstearamide (stearyl stearamide, CAS 13276 -08 -9) was investigated in five tests.
The first study comprises a test according to OECD guideline 301 D and a repetitive die away test following DGXI/400/84, EEC 1984 (Balk, 1989). Both tests were carried out under GLP and have a test duration of 6 weeks. In the OECD closed bottle test 2.04 mg/L of the substance was incubated with domestic activated sludge. The substance reached 8% degradation after 28 days and 9% degradation after 42 days. In the die away test 40 mg/L of the substance was incubated with industrial non-adapted activated sludge as inoculum. Degradation rates were 23% after 28 days and 29% after 42 days. The second study is a closed bottle test equivalent to the guideline L251, 1984.09.19, Part C, EEC 1984 (van Ginkel, 1988). Domestic activated sludge was used as inoculum and incubated with 2 mg/L of the substance. The degradation after 28 days was < 10%. The third study comprises two tests according to OECD guidelines 301 D and 301 F (Kolvenbach, 1989) using effluent from a municipal waste water treatment plant as inoculum. The closed bottle test applying 1.8 ppm of the substance resulted in 20% degradation after 28 days. The CO2 evolution test applying 10 and 20 ppm of the substance resulted in maximum degradation rates of 24% with non-adapted inoculum and 19% with adapted inoculum. Altogether it is stated that the substance can be regarded as not readily biodegradable under OECD criteria.
Reference
Description of key information
Not readily biodegradable: < 10% - 24% degradation (OECD 301 D, 301 F, DGXI/400/84 EEC 19984, L251, 1984.09.19, Part C, EEC 1984)
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
Studies on the ready biodegradability of (Z)-N-octadecyldocos-13-enamide (CAS No. 10094-45-8) are not available. Therefore data of the analogue substanceN-octadecylstearamide (stearyl stearamide, CAS 13276-08-9) were used as read-across.The read-across is justified due to the structural similarity of the analogue substances and similar physico-chemical properties resulting in a similar environmental fate and ecotoxicity profile.This read-across is in accordance with Regulation (EC) No. 1907/2006 Annex XI, 1.5 and justified in detail in the overall summary (IUCLID Chapter 6.1) and within the category justification attached in IUCLID Section 13. The ready biodegradability of N-octadecylstearamide (stearyl stearamide, CAS 13276-08-9) was investigated in five tests.
The first study comprises a test according to OECD guideline 301 D and a repetitive die away test following DGXI/400/84, EEC 1984 (Balk, 1989). Both tests were carried out under GLP and have a test duration of 6 weeks. In the OECD closed bottle test 2.04 mg/L of the substance was incubated with domestic activated sludge. The substance reached 8% degradation after 28 days and 9% degradation after 42 days. In the die away test 40 mg/L of the substance was incubated with industrial non-adapted activated sludge as inoculum. Degradation rates were 23% after 28 days and 29% after 42 days. The second study is a closed bottle test equivalent to the guideline L251, 1984.09.19, Part C, EEC 1984 (van Ginkel, 1988). Domestic activated sludge was used as inoculum and incubated with 2 mg/L of the substance. The degradation after 28 days was < 10%. The third study comprises two tests according to OECD guidelines 301 D and 301 F (Kolvenbach, 1989) using effluent from a municipal waste water treatment plant as inoculum. The closed bottle test applying 1.8 ppm of the substance resulted in 20% degradation after 28 days. The CO2 evolution test applying 10 and 20 ppm of the substance resulted in maximum degradation rates of 24% with non-adapted inoculum and 19% with adapted inoculum. Altogether it is stated that the substance can be regarded as not readily biodegradable under OECD criteria.
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