Registration Dossier
Registration Dossier
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EC number: 204-435-9 | CAS number: 120-92-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibitory effect of Cyclopentanone on the respiration rate of aerobic wastewater microorganisms of activated sludge was investigated in a 3-hour respiration inhibition test (OECD 209 and EU C11) under GLP. The nominal concentrations tested were: 10, 32, 100, 320 and 1000 mg/L.
Up to and including the highest concentration of 1000 mg/l, the test item had no significant inhibitory effect (15%) on the respiration rate of activated sludge after the incubation period of three hours. Thus, the 3-hour NOEC (EC15) of Cyclopentanone to activated sludge microorganisms was at least 1000 mg/L. This value might even be higher, but concentrations above 1000 mg/L were not tested. The 3-hour EC20, EC50 and EC80 could not be calculated, but were clearly higher than 1000 mg/L.
Key value for chemical safety assessment
Additional information
Five others studies (reliability 3) were also available but were not taken into consideration, because they were poorly described or did not follow recognized guidelines.
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