Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

The test substance indicated a positive response and had a calculated EC3 of 2% or 500 ug/cm2 in an O.E.C.D. test guideline 429 Local Lymph Node Assay. Therefore, the test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers is considered to be a skin sensitizer.


Migrated from Short description of key information:
The test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers was evaluated for skin sensitizing potential in an O.E.C.D. test guideline 429 Local Lymph Node Assay.

Respiratory sensitisation

Endpoint conclusion
Additional information:
Migrated from Short description of key information:
No data

Justification for classification or non-classification

Based on the outcome of an LLNA study demonstrating that the test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers is a skin sensitiser, Classification as Category I, "May cause an allergic skin reaction" is appropriate.