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EC number: 500-180-5 | CAS number: 67989-52-0
The test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers was evaluated for eye and skin irritating potential in O.E.C.D. test guideline 404 and 405 studies with GLP compliance.
The test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers was evaluated for skin irritation potential in an O.E.C.D. Test Guideline no 404 study. The Primary Irritation Index of 0 observed in the suggests that the test substance is "not irritanting" to the skin. The study data does not support Classification and Labeling as a skin irritant.
The test substance, 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers was accesed for eye irritation potential in an O.E.C.D. test guideline no. 405 study. The test substance was mildly irritating to the rabbit eye under the conditions of the study. However, the study data does not support Classification and Labeling as an eye irritant.
The test substance was not irritating to the rabbit eye or skin when tested by O.E.C.D. test guideline methods. The test item produced a maximum group mean score of 9.0 out of 110 and was classified as a mild irritant (Class 4 on a 1 to 8 scale) to the rabbit eye according to a modified Kay and Calandra classification system.
The data from standard O.E.C.D. test guideline studies demonstrates that the test substance is not irritating. No Classification and Labeling for irritation is required.
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