Registration Dossier

Manufacture, use & exposure

Manufacture

Documentsopen allclose all

Manufacture

Contributing activity / technique for the environment
Environmental release category (ERC):
ERC1: Manufacture of the substance
Contributing activity / technique for workersopen allclose all
Process category (PROC):
PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
Process category (PROC):
PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
Process category (PROC):
PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
Process category (PROC):
PROC 4: Chemical production where opportunity for exposure arises
Process category (PROC):
PROC 5: Mixing or blending in batch processes
Process category (PROC):
PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Process category (PROC):
PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
Process category (PROC):
PROC 15: Use as laboratory reagent

Manufacture

Contributing activity / technique for the environmentopen allclose all
Environmental release category (ERC):
ERC1: Manufacture of the substance
Name of activity / technique:
Environmental release during manufacture of Guanidine hydrochloride in (semi-)closed systems
Contributing activity / technique for workersopen allclose all
Process category (PROC):
PROC 4: Chemical production where opportunity for exposure arises
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Process category (PROC):
PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
Process category (PROC):
PROC 15: Use as laboratory reagent
Name of activity / technique:
Manufacturing of Guanidine hydrochloride in batch or other processes (synthesis)
Process category (PROC):
PROC 4: Chemical production where opportunity for exposure arises
Name of activity / technique:
Transfer of Guanidine hydrochloride at dedicated facilities
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Name of activity / technique:
Transfer of Guanidine hydrochloride into small containers at dedicated facilities
Process category (PROC):
PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
Name of activity / technique:
Laboratory analyses of samples containing Guanidine hydrochloride
Process category (PROC):
PROC 15: Use as laboratory reagent
Related assessment:
use assessed in an own CSR

Contributing scenario for the environment (related to workers activities)

Conditions of use for the environment

Amounts used, frequency and duration of use (or from service life)

Other conditions

Conditions and measures related to Biological Sewage Treatment Plant

Biological Sewage Treatment Plant (STP):
yes
Application of site specific biological STP sludge on agricultural soil:
yes

Conditions and measures related to external treatment of waste (including article waste)

Other conditions of use

Other conditions affecting environmental exposure

Other conditions of use

Releases to waste and the environment

Release to the environment

ReleaseEnvirRepopen allclose all
Release from the site to::
surface water
Release estimation method:
ERC
Remarks:
ERC-1
Release from the site to::
ambient air
Release estimation method:
measured release rate
Remarks:
Realistic release
Release from the site to::
non-agricultural soil
Release estimation method:
ERC
Remarks:
ERC-1

Release to external waste

Exposure of the environment

PECopen allclose all
Exposed compartment:
freshwater
Exposed compartment:
sediment (freshwater)
Exposed compartment:
marine water
Exposed compartment:
sediment (marine water)
Exposed compartment:
predators' prey (freshwater)
Exposed compartment:
predators' prey (marine water)
Exposed compartment:
top predators' prey (marine water)
Exposed compartment:
sewage treatment plant
Exposed compartment:
agricultural soil
Exposed compartment:
predators' prey (terrestrial)
Exposed compartment:
air

Exposure of humans via the environment

Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
ContribScenWorkersRepopen allclose all

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

OtherProdCharRepopen allclose all

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechCondRepopen allclose all
Effectiveness
Route affected:
inhalation

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
dermal
Effectiveness
Route affected:
inhalation

Other conditions affecting workers exposure

Place of use:
indoor
OtherCondRepopen allclose all

Exposure of workers

ExpEstopen allclose all
Type of exposure:
inhalation (internal) long-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
inhalation (internal) short-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
inhalation (external) long-term exposure
Type of exposure:
inhalation (external) short-term exposure
Type of exposure:
dermal (internal) long-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
dermal (internal) short-term exposure
Type of exposure:
dermal (external) long-term exposure
Type of exposure:
dermal (external) short-term exposure

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

OtherProdCharRepopen allclose all

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechCondRepopen allclose all
Effectiveness
Route affected:
inhalation

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
dermal
Effectiveness
Route affected:
inhalation

Other conditions affecting workers exposure

Place of use:
indoor
OtherCondRepopen allclose all

Exposure of workers

ExpEstopen allclose all
Type of exposure:
inhalation (internal) long-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
inhalation (internal) short-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
inhalation (external) long-term exposure
Type of exposure:
inhalation (external) short-term exposure
Type of exposure:
dermal (internal) long-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
dermal (internal) short-term exposure
Type of exposure:
dermal (external) long-term exposure
Type of exposure:
dermal (external) short-term exposure

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

OtherProdCharRepopen allclose all

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechCondRepopen allclose all
Effectiveness
Route affected:
inhalation

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
dermal
Effectiveness
Route affected:
inhalation

Other conditions affecting workers exposure

Place of use:
indoor
OtherCondRepopen allclose all

Exposure of workers

ExpEstopen allclose all
Type of exposure:
inhalation (internal) long-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
inhalation (internal) short-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
inhalation (external) long-term exposure
Type of exposure:
inhalation (external) short-term exposure
Type of exposure:
dermal (internal) long-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
dermal (internal) short-term exposure
Type of exposure:
dermal (external) long-term exposure
Type of exposure:
dermal (external) short-term exposure

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

OtherProdCharRepopen allclose all

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechCondRepopen allclose all
Effectiveness
Route affected:
inhalation

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
dermal
Effectiveness
Route affected:
inhalation

Other conditions affecting workers exposure

Place of use:
indoor
OtherCondRepopen allclose all

Exposure of workers

ExpEstopen allclose all
Type of exposure:
inhalation (internal) long-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
inhalation (internal) short-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
inhalation (external) long-term exposure
Type of exposure:
inhalation (external) short-term exposure
Type of exposure:
dermal (internal) long-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers v3
Type of exposure:
dermal (internal) short-term exposure
Type of exposure:
dermal (external) long-term exposure
Type of exposure:
dermal (external) short-term exposure