Registration Dossier
Registration Dossier
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EC number: 601-431-2 | CAS number: 1164-92-7
Endpoint summary
Administrative data
Description of key information
Oral (Rat, GLP, not audited report; OECD 423): LD50 > 2000 mg/kg
[Schering AG, Report X235; 1997-08-15]
Dermal (Rat, GLP, not audited report; OECD 402): LD50 > 2000 mg/kg
[Schering AG, Report X296; 1998-09-24]
Key value for chemical safety assessment
Additional information
The single oral administration of ZK 5180 to 3 male and 3 female rats at a dose of 2000 mg/kg was tolerated without compound-related clinical findings. No substance-related macroscopic pathological signs were observed. The acute oral toxicity of ZK 5180 in rats is above 2000 mg/kg body weight. [Schering AG, Report No X235; 1997 -08 -15]
The single dermal administration of ZK 5180 to 3 male and 3 female rats at a dose of 2000 mg/kg was tolerated without any compound-related clinical or macroscopic pathological signs. The acute dermal toxicity of ZK 5180 in rats is above 2000 mg/kg body weight. [Schering AG, Report X296; 1998-09-24]
Justification for classification or non-classification
Since LD50 > 2000 mg/kg after oral administration, there is no classification required according to Directive 67/548/EEC and Regulation (EC) 1272/2008 (CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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