Registration Dossier

Toxicological information

Sensitisation data (human)

Currently viewing:

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Results from a review
Cross-reference
Reason / purpose:
read-across: supporting information

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2008

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
Principles of method if other than guideline:
Human repeated insult patch test
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Method

Type of population:
not specified
Controls:
No data
Route of administration:
dermal

Results and discussion

Results of examinations:
No data

Any other information on results incl. tables

No data

Applicant's summary and conclusion

Conclusions:
In a human repeated insult patch test, the NOEL (highest concentration tested with no sensitization in human) was 10000 µg/cm².
Executive summary:

The NOEL (highest concentration tested with no sensitization in human), based on Human Repeated Insult Patch Test, was 10000 µg/cm². This value is very close to LLNA weighed mean EC3 values from five LLNA studies (=10075 µg/cm²).