Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-424-3 | CAS number: 95-49-8
Endpoint summary
Administrative data
Description of key information
See section "Additional information" below.
Additional information
The short-term toxicity of 1-chloro-2-methylbenzene towards fish was tested following the OECD Guideline 203 yielding a LC50 (96h; Oryzias latipes; analytically confirmed) of 7.7 mg/L (MOE Japan, 2001).
The short-term toxicity of 1 -chloro-2 -methylbenzene towards aquatic invertebrates is characterized by an EC50 (Daphnia magna; immob.; 48 h; semi-stat.; geom. mean meas.) = 0.70 mg/L (95% CI: 0.482 - 0.889) having Daphnia magna as test species (MOE Japan, 2001).
The long-term toxicity of 1 -chloro-2 -methylbenzene towards aquatic invertebrates was investigated following OECD TG 211 (1998). Daphnia magna was used as test organism yielding a 21-day NOEC of 0.313 mg/L (TWM) for reproduction as well as parental mortality (MOE Japan, 2001).
The toxicity of 1-chloro-2-methylbenzene towards aquatic algae is characterized by an ECr50(72 h; growth rate; geom. mean meas.) of 9.11 mg/L (95% confidence limit: 8.71 - 9.52), and an EC10(72 h; growth rate; geom. mean meas.) of 6.09 mg/L (95% confidence limit: 5.92 - 6.26) (MOE Japan, 2001).
The toxicity of 1 -chloro-2 -methylbenzene towards microorganisms was tested using Pseudomonas putida as test species. An EC3(16 h) of 15 mg/L was observed having the inhibition of cell multiplication inhibition as endpoint (Bringmann, 1977, 1979, 1980).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
