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EC number: 252-899-6
CAS number: 36177-92-1
The skin sensitizing potential of the substance was investigated in a
Guinea Pig Maximization Test.
Based on the results of an irritation screening study the test item was
administered as 0.1% (w/v) mixture in sterile water and in 1:1
FCA/sterile water for the intradermal injection phase, as a 5% (m/v)
mixture in sterile water for the topical induction phase, and as a 1%
mixture for the challenge application phase in the definitive study.
Twenty animals were assigned to the test group and 10 animals were
assigned to the irritation control group (negative control).
None of the animals in the test or the irritation control group
exhibited a dermal reaction to the challenge application of the test
Therefore, based on the outcome of the available Guinea Pig Maximization
Test, the substance is not considered to be a skin sensitizer.
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