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Key value for chemical safety assessment

Additional information

Based on the composition of the substance (Mg3K[AlF2O(SiO3)3]) a mutagenic potential of Fluorphlogopite was not expected.

This was confirmed by 3 in vitro studies which were all negative (not mutagenic). All studies were GLP compliant and of high quality (Klimisch score = 1). There is no reason to believe that these results would not be applicable to humans.

Justification for selection of genetic toxicity endpoint
No study was selected, since all three in vitro studies were negative.

Short description of key information:
Clearly negative in vitro studies - both with and without metabolic activation.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Fluorphlogopite is not classified with regard to genetic toxicity.

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