Registration Dossier

Administrative data

Description of key information

Skin irritation / corrosion, OECD404: not irritating
Eye irritation: OECD405: not irritating

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

In an in vivo skin irritation/corrosion study (GLP, OECD404) all areas treated with the test substance were normal at each observation time. The test substance was not irritating to the skin.

 

In an in vivo eye irritation study (GLP, OECD405) the test substance caused slight transient ocular irritation. Based on the mean scores calculated from the individual examinations performed 24, 48 and 72 h p.a. and referring to Commission Directive 2001/59/EC the test substance did not require classification for eye irritation.

Justification for classification or non-classification

According to the results of an in vivo skin irritiation/corrosion study and an in vivo eye irritaiton study the test substance does not require classification.