Registration Dossier
Registration Dossier
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EC number: 203-585-2 | CAS number: 108-46-3
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Resorcinol does not meet the criteria, as defined by ECHA, for designation as persistent, bioaccumulative or toxic (PBT) substance. In accordance with ECHA Guidance document R.11 and Part C, further assessment is not necessary.
Persistence:
Resorcinol is not considered to be persistent in the environment. The substance is considered biodegradable under aerobic conditions. Several aerobic biodegradation studies are available following inherent and readily biodegradation protocols. In a MITI test following OECD Test guideline 301C, Resorcinol was determined to be readily biodegradable with elimination rates being 66.7% after 14 days. In the study conducted following OECD Test guideline 302B, 97% degradation was observed after 4 days. In addition, the substance does not undergo hydrolysis as it contains no functional groups susceptible to hydrolysis under environmentally relevant pH and temperature conditions (Harris, J. (1990) and US EPA (2009)).
Bioaccumulation:
Based on the physical chemical properties of the substance, it is not expected to bioaccumulate, as the Log Kow is 0.8 and the BCF is 3.16, which is well below the value(s) established by the ECHA. In addition, data are provided in the toxicity section in regards to typical aquatic species. Additional data from the terrestrial compartment and metabolism data from animals and humans are available which support a rapid elimination of the test substance with at least 98% elimination. In some cases, greater than 98% elimination is noted.
Toxicity:
Based on available data the most sensitive species in both acute and chronic aquatic toxicity tests is the aquatic invertebrate, Daphnia magna. The lowest NOEC available is from the 21-day study in which the highest dose tested serves as the NOEC, 0.172 mg/L. When comparing this value with the toxicity criteria as identified by ECHA, Resorcinol is not considered toxic.
- Likely routes of exposure:
Resorcinol does not meet the criteria, as defined by ECHA, for designation as persistent, bioaccumulative or toxic (PBT) substance. In accordance with ECHA Guidance document R.11 and Part C, further assessment is not necessary.
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