Registration Dossier

Ecotoxicological information

Toxicity to birds

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Data generated from the Acute Lethal Dose suggest that birds are less sensitive to acute oral exposures to RDX than mammals. The Acute Lethal Dose for quail was 187 to 280 mg/kg/d, while for mammals, the acute oral median lethal dose ranged from 71 to 118 mg RDX/kd/d.
Data from the 14-d dietary trial suggested that RDX exposure inhibited food consumption, weight gain, and egg production. Dietary RDX exposure for 90-d produced a dose-dependant decreasing trend in total feed consumption, total egg production, and hen-housed production parameters.

Key value for chemical safety assessment

Long-term EC10, LC10 or NOEC for birds:
8.7 mg/kg food

Additional information