4,5-dihydroxy-1,3-dimethylimidazolidin-2-one

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

self-heating substances / mixtures

Data waiving:

study technically not feasible

Justification for data waiving:

the study does not need to be conducted because the substance is completely molten at 160°C

Reference 2

Endpoint:

pyrophoric liquids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is a solid

Reference 3

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the experience in production or handling shows that the substance does not react with water, e.g. the substance is manufactured with water or washed with water

Reference 4

Endpoint:

pyrophoric solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied

Reference 5

Endpoint:

flammable gases

Data waiving:

study technically not feasible

Justification for data waiving:

the study does not need to be conducted because the substance is a liquid

Reference 6

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

GLP compliance:

yes (incl. QA statement)

Key result

Test procedure:

other: not specified

Remarks on result:

other: No ignition on contact with air. Not a readily combustible solid

Preliminary test; Brief burning and rapid extinction was observed.

Main test: Omitted due to result of preliminary test.

Interpretation of results:

GHS criteria not met

Description of key information

non flammable
The substance has no pyrophoric properties and does not liberate flammable gases on contact with water.

Key value for chemical safety assessment

Flammability:

non flammable

Additional information

Flammable gases

The test item is a solid (100% substance) or a liquid (aqueous solution) at ambient conditions. This hazard class is only applicable for gases. Thus, the substance was not considered for classification as flammable gas.

 

Flammable solid

The test item is a solid (100% substance) or a liquid (aqueous solution) at ambient conditions. This hazard class is only applicable for solids.The test item was not readily combustible.

 

Flammable liquids

The test item is a solid (100% substance) or a liquid (aqueous solution) at ambient conditions. This hazard class is only applicable for liquids. An 41% aqueous solution of the test item is non-flammable.

 

Pyrophoric liquids

In accordance with section 2.9.4 Annex I of Regulation (EC) No 1272/2008 and ECHA guidance on the application of CLP Criteria section 2.9.4.2 the classification procedure for pyrophoric liquids needs not to be applied when experience in manufacture or handling shows that the liquid does not ignite spontaneously on coming into contact with air at normal temperatures (i.e. the liquid is known to be stable at room temperature for prolonged periods of time (days)). Based on the experience in handling and use the substance is not known to ignite spontaneously when coming into contact with air at normal temperatures. Thus, no study was conducted and the substance was not considered for classification as pyrophoric liquid.

 

Pyrophoric solids

In accordance with section 2.10.4 of Annex I of Regulation (EC) No 1272/2008 and ECHA guidance on the application of CLP Criteria section 2.9.4.2 the classification procedure for pyrophoric solids needs not to be applied when experience in manufacture or handling shows that the solid does not ignite spontaneously on coming into contact with air at normal temperatures (i.e. the liquid is known to be stable at room temperature for prolonged periods of time (days)). Based on the experience in handling and use the substance is not known to ignite spontaneously when coming into contact with air at normal temperatures. Thus, no study was conducted and the substance was not considered for classification as pyrophoric solid.

 

Self-heating substances and mixtures

In accordance with ECHA guidance on IR/CSA chapter R.7a section R7.1.10.7 the test does not to be conducted as the substances has a melting point below 160°C. Furthermore, according to Annex VII of REACH and ECHA guidance on IR/CSA chapter R.7a section R7.1.10.7, no test has to be conducted if preliminary results exclude self-heating of the substance up to 400°C. As shown in IUCLID section 4.12, no self-heating was detected up to the melting point at 131°C.

 

Substances which, in contact with water, emit flammable gases

In accordance with column 2 of REACH Annex VI and with Regulation (EC) No 1272/2008 Annex I section 2.12.4 and ECHA guidance on the application of CLP Criteria section 2.12.4.2 the classification procedure for this hazard class needs not to be applied. Because the substance is known to be soluble in water to form a stable mixture and in addition the test substance is not pyrophoric. Thus, no study was conducted and the substance was not considered for classification.

 

Flammable Aerosols

Section 2.4.2 of Guidance on the application on the CLP Criteria state as follows: “Aerosols, this means aerosol dispensers, are any non-refillable receptacles made of metal, glass or plastics and containing a gas compressed, liquefied or dissolved under pressure, with or without a liquid, paste or powder, and fitted with a release device allowing the contents to be ejected as solid or liquid particles in suspension in a gas, as a foam, paste or powder or in a liquid state or in a gaseous state." Thus, as the substance does not meet the definition for aerosol, the test for aerosols was waived. Consequently the substance has not to be considered for classification for this hazard class.

 

In conclusion, the substance has not to be considered as flammable gas, flammable liquid, flammable solid, flammable in contact with water, flammable aerosol, pyrophoric solid, pyrophoric liquid or self-heating substance.

Justification for classification or non-classification

Classification, Labelling, and Packaging Regulation (EC) No. 1272/2008

In accordance with Annex I Section 2.2, Section 2.3, Section 2.7, Section 2.9, Section 2.10 Section 2.11, Section 2.12 of Regulation (EC) No 1272/2008, as amended for the eighteenth time in Regulation (EU) 2022/692, and UN GHS Rev 8 (2019) the test item has not to be classified as readily combustible solid in class 4 Division 4.1, flammable liquid, self-heating substance in Class 4 Division 4.2, substances which in contact with water emit flammable gases in Class 4 Division 4.3, pyrophoric liquid, pyrophoric solid in class 4 Division 4.2, flammable gases in class 2 or as aerosol in class 2.