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Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature

Data source

Reference
Reference Type:
review article or handbook
Title:
4 Final Report on the Safety Assessment of Isostearic Acid
Author:
Cosmetic Ingredient Review (CIR)
Year:
1983
Bibliographic source:
Journal of the American College of Toxicology 2(7):61-74

Materials and methods

Type of study / information:
Clinical Assessment of Safety: Primary Skin Irritation
Endpoint addressed:
skin irritation / corrosion
Principles of method if other than guideline:
24 h occlusive patch test
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Isostearic Acid
- Analytical purity: no data

Method

Details on study design:
A 24 h occlusive patch test procedure was used to evaluate the primary skin irritation caused by undiluted lsostearic Acid.
Exposure assessment:
not specified

Results and discussion

Results:
The undiluted ingredient tested “negative” in the single insult patch test.

Applicant's summary and conclusion

Conclusions:
not irritating