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EC number: 250-178-0 | CAS number: 30399-84-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No toxicological effects were observed within the water solubility of Isooctadecanoic acid, therefore LC50 (96 h) will be higher than the water solubility limit (0.24 mg/L).
Key value for chemical safety assessment
Additional information
One study investigating the short-term toxicity to freshwater fish of Isooctadecanoic Acid (CAS No. 30399-84-9) is available. This test was conducted in accordance to a German standard test for the evalulation of water-polluting substances (Bewertung wassergefährdender Stoffe, Bestimmung der akuten Fischtoxozität), which is comparable to DIN 38412 L15 under static test conditions with the freshwater fish Cyprinus carpio (Bogers, 1988). Tween 80 was used as solubiliser in order to obtain a homogenous dispersion of the test substance in water. Furthermore the test duration was only 48 instead of 96 hours. An LC50 of 13.4 mg/L after 48 hours and a NOEC of 5.6 mg/L was determined. One might expect that the LC50 after 96 hours will be lower, however, as the water solubility of the test substance is only 0.24 mg/L, it can be assumed that the LC50 (96 h) will be higher than the water solubility limit of isooctadecanoic acid.
This finding is supported by further data within subcategory 1 (monomers) of the dimerised fatty acids and its derivatives. For Fatty acids, C16-18 and C18-unsatd., branched and linear the semi-static short term test with freshwater fish (Leuciscus idus) according to OECD guideline 203 showed no mortality within the tested concentrations. Due to the low water solubility of Fatty acids, C16-18 and C18-unsatd., branched and linear the test solutions were prepared as Water Accommodated Fractions (WAF). No mortality up to the limit of the water solubility of the test substance was observed. The LL50 (96h) is > 1000 mg/L and the NOELR ≥ 1000 mg/L (Sewell, 1994).
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