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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1989
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: In test report is mentioned that the study was performed according to EEC-Guideline 88/302 Part C and therefore according to OECD Guideline 209 but no GLP. Not well documented.
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1989
Report date:
1989

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
DIN 38412-8 (Pseudomonas Zellvermehrungshemmtest)
Deviations:
not specified
Principles of method if other than guideline:
No data.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2'-chloroacetoacetanilide
EC Number:
202-269-1
EC Name:
2'-chloroacetoacetanilide
Cas Number:
93-70-9
Molecular formula:
C10H10ClNO2
IUPAC Name:
2'-chloroacetoacetanilide
Details on test material:
Substance: Acetessig-o-chloranilid TTR

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
activated sludge

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
3 h

Results and discussion

Effect concentrations
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
growth inhibition

Any other information on results incl. tables

EC20 = 517.6 mg/L

EC80 > 1000 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
no
Conclusions:
At the tested concentration no significant inhibition could be observed, EC50 > 1000 mg/L.
Executive summary:

Study report is not well documented and most of the information regarding test procedure is missing, therefore the validity criteria are not entirely fulfilled.

At the tested concentration no significant inhibition could be observed, EC50 > 1000 mg/L.