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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

With high probability not harmful to fish.

Key value for chemical safety assessment

Additional information

The acute toxicity of retinyl palmitate to fish was not investigated. However, the structural analogue retinyl propionate (CAS 7069-42-3) was tested in a screening test performed according to a GLP DIN 38 412 (part L15) study. The susbstance showed no toxicity up to the highest test concentration of 10000 mg/L (LC50 > 10000 mg/L). Based on this result and the fact that the water solubility of retinyl palmitate is below 1 mg/L at 20°C (calculated value: 2.8E-11 mg/L at 25 °C) acute toxicity to fish is unlikely.