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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

To determine the toxicity of p-nonylphenol-formaldehyde-diethanolamine, Mannich base  to STP microorganisms, a GLP-compliant activated sludge respiration inhibition test was performed in accordance with OECD Guideline 209 (Toxi-Coop Zrt. 2013). The inhibitory effect of the test substance on activated sludge microorganisms respiration was tested at concentrations of 0, 10, 20, 40, 80 and 160 mg/L. The inhibition of the specific respiration rates compared to blank controls showed clear dose-related tendency with inhibitions of 7.0% at 20 mg/L, 16.1% at 40 mg/L, 35.5% at 80 mg/L and 73.8% at 160 mg/L. Based on these data, the 3-h EC50 and EC10 values are determined at 114.2 mg/L and 31.4 mg/L, respectively.

Key value for chemical safety assessment

EC50 for microorganisms:
114.2 mg/L
EC10 or NOEC for microorganisms:
31.4 mg/L

Additional information