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Diss Factsheets
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EC number: 284-892-9 | CAS number: 84989-04-8 The fraction of tar acid rich in 3- and 4-methylphenol, recovered by distillation of low-temperature coal tar crude tar acids.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Type of information:
- other: surveillance
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: no data on exposure time
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
- Study type:
- health record from industry
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: german Gefahrstoffverordnung §16(2)
- Principles of method if other than guideline:
- Occupational medical surveillance
- GLP compliance:
- not specified
Test material
- Reference substance name:
- o-, m- and p-cresol
- IUPAC Name:
- o-, m- and p-cresol
- Details on test material:
- (no further data)
Constituent 1
Method
- Details on study design:
- medical examination of the staff includes e.g. medical history, physical examination, lung function, ECG/Ergometry, vision testing, audiometry, laboratory examinations of blood and urine
biomonitoring: determination of cresols in urine of workers
Results and discussion
- Results:
- see section: remarks on results including tables and figures
Any other information on results incl. tables
The results of the measurements show that the concentration of cresols in the air on workplaces fall below the OEL
The maximum cresol concentration from 2003 to 2008 was 0.9 mg/m³.
Occupational medical surveillance did not reveal any health effects like irritaion of the skin, mucosa membranes or upper respiratory tract which could be derived to be from a possible cresol exposure at workplace.
Biomonitoring showed that in case of routine handling of cresols with required protection devices cresol concentrations were in all cased below the limiting value.
Applicant's summary and conclusion
- Executive summary:
Occupational medical surveillance of a plant in Germany did not report of complaints from irritational effects from workers. The maximal concentration in the air was 0.9 mg/m³ and is regarded to be the NAEC (Currenta 2008)
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