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Short-term toxicity to aquatic invertebrates

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Description of key information

Hydrolysis product ethanol: With high probability acutely not harmful to aquatic invertebrates.
Hydrolysis product HCl: Acutely very toxic for aquatic invertebrates (pH dependent).

Key value for chemical safety assessment

Additional information

There are no data available regarding the toxic effect of the parent compound to aquatic invertebrates. The hydrolysis product ethanol was tested in a acute toxicity test with Ceriodaphnia dubia following ASTM Standard E729 -80. The resulting EC50 (48 h) was 5012 mg/L, indicating no harmful effects (OECD, 2005).

The hydrolysis product HCl showed acutely very toxic effects due to low pH: EC50 (48 h) = 0.492 mg/L (OECD, 2002).





Ceriodaphnia dubia

EC50 (48 h) = 5012 mg/L (nominal); ASTM Standard E729-80

Hydrolysis product ethanol; reliability: 2, key study

OECD, 2005

Daphnia magna


EC50 (48 h) = 0.492 mg/L (acid equivalent to pH 5.3), semi-static, with analytical monitoring, OECD TG 202

Hydrolysis product HCl; reliability: 2

OECD, 2002