Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Basic toxicokinetics

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Administrative data

Endpoint:
basic toxicokinetics in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not translated, only short abstract available

Data source

Reference
Title:
No information
Author:
Mlynarczyk W, Cz Dadowski (2001). Toxicometric indices of mononitrotoluenes; Part IV. Toxicokinetics. Bromat. Chem. Toksykol. XXXIV, 315-320

Materials and methods

Objective of study:
toxicokinetics
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-nitrotoluene
EC Number:
201-853-3
EC Name:
2-nitrotoluene
Cas Number:
88-72-2
Molecular formula:
C7H7NO2
IUPAC Name:
1-methyl-2-nitrobenzene
Details on test material:
IUCLID4 Test substance: other TS: 2.nitrotoluene, 3-nitrotoluene, 4-nitrotoluene

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Toxicokinetic / pharmacokinetic studies

Toxicokinetic parametersopen allclose all
Toxicokinetic parameters:
half-life 2nd:
Toxicokinetic parameters:
half-life 1st:
Toxicokinetic parameters:
half-life 3rd:

Applicant's summary and conclusion