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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Remarks:
Data from reliable source, usually performing GLP-guideline studies, detailed documentation only available in Japanese.

Data source

Referenceopen allclose all

Reference Type:
other: J-CHECK
Title:
Unnamed
Year:
2019
Report date:
2019
Reference Type:
other: Japanese database
Title:
Unnamed
Year:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-xylidine
EC Number:
201-758-7
EC Name:
2,6-xylidine
Cas Number:
87-62-7
Molecular formula:
C8H11N
IUPAC Name:
2,6-dimethylaniline

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Oryzias latipes

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h

Test conditions

Test temperature:
24 +- 1 °C
Nominal and measured concentrations:
control, 100 mg/L (nominal values)
Details on test conditions:
TEST SYSTEM
- Test vessel: 3 L container
- No. of organisms per vessel: 10

OTHER TEST CONDITIONS
- Photoperiod: room light, 16 hours light - 8 hours dark

Reference substance (positive control):
not specified

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 98 mg/L
Nominal / measured:
meas. (geom. mean)
Basis for effect:
mortality (fish)
Remarks on result:
other:
Remarks:
Effect concentration was calculated based on geometric mean values which were calculated using measured values of renewal and old test solution.

Applicant's summary and conclusion