2,6-xylidine

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Remarks:

Data from reliable source, usually performing GLP-guideline studies, detailed documentation only available in Japanese.

Data source

Reference

Reference 1

Reference Type:

other: J-CHECK

Title:

Unnamed

Year:

2019

Report date:

2019

Reference 2

Reference Type:

other: Japanese database

Title:

Unnamed

Year:

2016

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 203 (Fish, Acute Toxicity Test)

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

2,6-xylidine

EC Number:

201-758-7

EC Name:

2,6-xylidine

Cas Number:

87-62-7

Molecular formula:

C8H11N

IUPAC Name:

2,6-dimethylaniline

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

not specified

Test organisms

Test organisms (species):

Oryzias latipes

Study design

Test type:

semi-static

Water media type:

freshwater

Limit test:

yes

Total exposure duration:

96 h

Test conditions

Test temperature:

24 +- 1 °C

Nominal and measured concentrations:

control, 100 mg/L (nominal values)

Details on test conditions:

TEST SYSTEM
- Test vessel: 3 L container
- No. of organisms per vessel: 10

OTHER TEST CONDITIONS
- Photoperiod: room light, 16 hours light - 8 hours dark

Reference substance (positive control):

not specified

Results and discussion

Effect concentrations

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

> 98 mg/L

Nominal / measured:

meas. (geom. mean)

Basis for effect:

mortality (fish)

Remarks on result:

other:

Remarks:

Effect concentration was calculated based on geometric mean values which were calculated using measured values of renewal and old test solution.