Registration Dossier
Registration Dossier
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EC number: 284-664-9 | CAS number: 84961-74-0
Endpoint summary
Administrative data
Description of key information
Additional information
LAS-IPA is readily biodegradable. No studies on degradation of LAS-IPA in water-sediment or in soil are available. In accordance with column 2 of REACH Annex IX, the water and sediment simulation test and biodegradation test in soil do not need to be conducted. Supporting studies are also available for read-across substances, such as LAS-Na and IPA, where the biodegradation of LAS-IPA may be further described by the biodegradation of LAS-Na and IPA according to the read-across statement in which full dissociation of the LAS-IPA in water is supported. Both read-across substances are also readily biodegradable. It is concluded that indirect exposure to the soil compartment from LAS-IPA via sludge application is unlikely.
LAS-Na
Biodegradation of the read-across substance LAS-Na in sediment is rapid.Mineralization (14CO2 production) was best described by a First Order Model (r2 > 0.99), indicating that parent and metabolites were equally bioavailable to undergo mineralization. The rate constant for mineralization was 0.06 day-1. Half-life in sludge-amended soil after application of sludge of LAS-Na was >7 to <22 days based on recovered LAS-Na.
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