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Physical & Chemical properties

Dissociation constant

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Description of key information

The pKa of the constituents of Alcohols, C12-15, branched and linear is predicted to be 15.8 using a reliable freely-available method. 

Key value for chemical safety assessment

Additional information

No measured data for dissociation constant of the constituents of Alcohols, C12-15, branched and linear were available. The pKa value (normal conditions) was predicted using SPARC.

While the hydroxyl group is ionisable, aliphatic alcohols are extremely weak acids and only dissociate under strongly basic conditions. In the range of pH usually considered relevant to the human body and environment, i.e. pH 2-9, the constituents of Alcohols, C12-15, branched and linear will be non-ionised. There is no need to conduct further testing.

Discussion of trends in the Category of C6-24 linear and essentially-linear aliphatic alcohols:

Measured data have not been collated. However, in general, long chain aliphatic alcohols are extremely weak acids and only dissociate under strongly basic conditions (pKa= 15.8). In the range of pH usually considered relevant to the human body and environment, i.e. pH 2-9, the substances of this Category will be non-ionised.