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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

In a GLP study conducted according to OECD guideline 301F, DEIPA was determined to be readily biodegradable (86%) in activated sludge in 28 days (Goodwin, 1999).

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

In a GLP study conducted according to OECD Guideline 301F, the ready biodegradability of DEIPA in activated sludge was assessed. The test mixture, comprising of 500 mL of inoculated mineral medium and 1 mL of the test substance at known concentration, was continuously stirred in darkness at a constant temperature over a period of 28 days. O2consumption was used as the primary indicator of biodegradation, by measuring the decrease in O2concentration in the headspace of the reaction vessel at 6-hr intervals. In addition, CO2production and the difference in dissolved organic carbon (DOC) were also determined. Based on O2consumption, DEIPA was determined to be 'readily biodegradable' as 10% degradation of DEIPA was achieved at 7.8 days and exceeded 60% within the subsequent 10-day window. Over the 28-day study, 86% biodegradation was seen (based on O2consumption). In addition, biodegradation measured in terms of CO2production and DOC removal were 68% and 91% respectively over the 28-day period. Based on the results of this reliable study, DEIPA can be considered as readily biodegradable in activated sludge in 28 days (Goodwin, 1999).

In summarising this study, NICNAS (2009) concluded that DEIPA was readily biodegradable.

In addition, DEIPA was calculated (in BIOWIN) to be readily biodegradable using the EPI Suite software (v 4.10) (US EPA, 2011).


NICNAS (2009). Australian National Industrial Chemicals Notification and Assessment Scheme. Full Public Report. DEIPA. File No: STD/1344. December 2009.