Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Two studies are available. Sasaki et al, 1982 determined BCF values in the range of 21-35 in Killifish and CITI, 1992 reported BCF values in the range of 5.5-20 in carp (6-8 weeks). The worst case approach (highest BCF of 35) was used to choose the key value for chemical safety assessment. Tributyl phosphate is thus considered as non-bioaccumulative in fish.

Additional information

The bioaccumulation of tributylphosphate was investigated in a continuous exposure system in Killifish (Sasaki et al, 1982). The test substance was taken up rapidly into the fish, reaching steady state within 24 hours. Levels remain constant for the remainder of the study. BCF values were calculated to be 21 -35. Following removal from the test water, elimination was rapid with a BH (biological half-life) value of 1.25 hours. Levels were below the lod at 24 hours.

The bioaccumulation of the substance from water was investigated in carp over a period of 6 -8 weeks (CITI, 1992). BCF values for fish of 6.9 -20 were calculated for the substance at a concentration of 6 µg/L in water; BCF values of 5.5 -10 were calculated for a concentration in water of 60 µg/L.