Registration Dossier
Registration Dossier
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EC number: 249-109-7 | CAS number: 28629-66-5
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
In a key study using the Magnusson-Kligman Guinea pig maximization test, 20 Dunkin-Hartley strain albino Guinea pigs were treated with 5% w/v test substance for both the induction and challenge phases (Costello BA, 1982). Scores of zero in all test animals were obtained at all points examined. The test substance does not appear to be a sensitizer in the albino guinea pig.
In a supporting study using the Magnusson-Kligman Guinea pig maximization test, 20 Dunkin-Hartley strain albino Guinea pigs were treated with 5% w/v test substance for both the induction and challenge phases (Costello BA and Gilman MR, 1982). Scores of zero in all test animals were obtained at all points examined. The test substance does not appear to be a sensitizer in the albino guinea pig.
Migrated from Short description of key information:
The substance is not skin-sensitizing to guinea gigs
Respiratory sensitisation
Endpoint conclusion
- Additional information:
no data available
Migrated from Short description of key information:
no data available
Justification for classification or non-classification
In accordance with EU CLP (Regulation (EC) No. 1272/2008), this substance does not meet the criteria for classification as a skin sensitizer.
No data are available for respiratory sensitization.
The substance is therefore not classifiable for this endpoint in accordance to the CLP Regulation (EC) No 1272/2008.
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