Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
4 µg/L
Assessment factor:
100
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
38 µg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
4.6 µg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
3 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.144 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.014 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.026 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
PNEC oral
PNEC value:
8.33 mg/kg food
Assessment factor:
300

Additional information

Conclusion on classification

Studies of this substance and an analog are available for evaluating biodegradation and toxicity to aquatic vertebrate and invertebrate species.

 

An analog of this substance, EC 224-235-5, is not biodegradable when tested in accordance with OECD 301D Hansonis-Joulah, 1992. The biological oxygen demand was less than 5% of the chemical oxygen demand in both test concentrations at all sampling dates.

 

The acute aquatic toxicity ofthis substancewas evaluated using rainbow trout and was conducted in accordance withOECD 203 (Wetton, PM, 2001). The 96 h LL (Lethal Loading Rate) 50 value of the substance was determined to be 3.8 mg/l. The No Observed Effect Loading rate was 1.8 mg/l loading rate WAF.

 

Then acute toxicity of this substance also was evaluated inDaphnia(OECD 202) (Wetton, PM, 2001). The 48-Hour EL*50 was determined to be 510 mg/L nominal loading rate and the No Observed Effect Loading rate was 180 mg/l nominal loading rate.

 

The acute toxicity of an analog of this substance, EC 224-235-5, was evaluated in freshwater algae in accordance with OECD Guideline 201 (Vryenhoef, H, 2004). Exposure ofScenedesmus subspicatusto the test material gave an EbL50 (72h) value of 240 mg/L loading rate WAF and an ErL50 (0-72hr) value of 410 mg/L loading rate WAF. The No Observed Effect Loading rate was 220 mg/L loading rate WAF.

 

The potential impact of this substance on microbial metabolism also was studied using the activated sludge respiration test in accordance with OECD 209 (Goodrich, MS, 1994). Based on the respiration rates of the sludge-associated microbes at five nominal exposure concentrations, the EC50 was calculated to be 300 mg/l.

 

Based on the available environmental fate and ecotoxicological data for daphnids, fish and algae, this substance has acute aquatic toxicity between 1-10mg/L in the most sensitive species, is not readily biodegradable, and has a measured log Kow of greater than 2.87, therefore, this substance requires classification to the aquatic environment according to Directive 67/548/EEC,  the EU CLP (Regulation (EC) No. 1272/2008) ( Aquatic Chronic Category 2).