Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 295-446-8 | CAS number: 92045-64-2 A complex combination of hydrocarbons obtained by the sorption of benzene from a catalytically fully hydrogenated benzene-rich hydrocarbon cut that was distillatively obtained from prehydrogenated cracked naphtha. It consists predominantly of paraffinic and naphthenic hydrocarbons having carbon numbers predominantly in the range of C6 through C7 and boiling in the range of approximately 70°C to 100°C (158°F to 212°F).
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
A total of 42 guinea pig sensitisaton studies were identified. In laboratory animals, neither gasoline nor naphtha blending streams induced dermal sensitization in Buehler tests in guinea pigs. In the human literature, there is no evidence of allergic contact dermatitis to either gasoline or naphtha blending streams.
Migrated from Short description of key information:
Skin sensitization – Not sensitizing in guinea pig (OECD TG 406).
Justification for selection of skin sensitisation endpoint:
One of 42 studies undertaken on low boiling point naphthas which showed similar results.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
Forty two animal sensitisation studies were identified which did not show evidence of dermal sensitisation.
Migrated from Short description of key information:
Results from a large number of guinea pig sensitisation studies do not show evidence of skin sensitisation,
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
