Registration Dossier

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary information, assigned as valid with restrictions in OECD SIDS

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
Mitsuboshi Chemical Co.
Bibliographic source:
unpublished data; cited in OECD SIDS for CAS No. 88-44-8, 2005

Materials and methods

Study type:
study with volunteers
Endpoint addressed:
skin irritation / corrosion
Test guideline
Qualifier:
according to
Guideline:
other: IMDG code (International Maritime Code for Dangerous Goods; 2002)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Source: Mitsuboshi Chemical Co., Ltd.
Purity: >99%

Method

Type of population:
general
Subjects:
5 males (age 27-48 years)
Route of exposure:
dermal
Reason of exposure:
intentional
Exposure assessment:
not specified
Details on exposure:
occlusive 50 mg/patch on an inner arm, for 6 hours; no vehicle was used

Results and discussion

Clinical signs:
not irritating

Applicant's summary and conclusion

Conclusions:
not irritating