Registration Dossier
Registration Dossier
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EC number: 201-831-3 | CAS number: 88-44-8
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: secondary information, assigned as valid with restrictions in OECD SIDS
Data source
Reference
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- Mitsuboshi Chemical Co.
- Bibliographic source:
- unpublished data; cited in OECD SIDS for CAS No. 88-44-8, 2005
Materials and methods
- Study type:
- study with volunteers
- Endpoint addressed:
- skin irritation / corrosion
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: IMDG code (International Maritime Code for Dangerous Goods; 2002)
Test material
- Reference substance name:
- 4-aminotoluene-3-sulphonic acid
- EC Number:
- 201-831-3
- EC Name:
- 4-aminotoluene-3-sulphonic acid
- Cas Number:
- 88-44-8
- Molecular formula:
- C7H9NO3S
- IUPAC Name:
- 2-amino-5-methylbenzene-1-sulfonic acid
- Details on test material:
- Source: Mitsuboshi Chemical Co., Ltd.
Purity: >99%
Constituent 1
Method
- Type of population:
- general
- Subjects:
- 5 males (age 27-48 years)
- Route of exposure:
- dermal
- Reason of exposure:
- intentional
- Exposure assessment:
- not specified
- Details on exposure:
- occlusive 50 mg/patch on an inner arm, for 6 hours; no vehicle was used
Results and discussion
- Clinical signs:
- not irritating
Applicant's summary and conclusion
- Conclusions:
- not irritating
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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