Registration Dossier
Registration Dossier
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EC number: 248-421-0 | CAS number: 27344-41-8
Toxicity to reproduction
Administrative data
- Endpoint:
- three-generation reproductive toxicity
- Remarks:
- based on test type (migrated information)
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Study performed at a discreditaed laboratory. IBT was known to have falsified test reports.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 973
- Report date:
- 1973
Materials and methods
- Principles of method if other than guideline:
- 3-Generation study
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- Disodium 2,2'-([1,1'-biphenyl]-4,4'-diyldivinylene)bis(benzenesulphonate)
- EC Number:
- 248-421-0
- EC Name:
- Disodium 2,2'-([1,1'-biphenyl]-4,4'-diyldivinylene)bis(benzenesulphonate)
- Cas Number:
- 27344-41-8
- Molecular formula:
- C28H22O6S2.2Na
- IUPAC Name:
- disodium 2,2'-(biphenyl-4,4'-diyldiethene-2,1-diyl)dibenzenesulfonate
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: feed
Doses / concentrations
- Remarks:
- Doses / Concentrations:
40, 200, or 1,000 ppm
Basis:
nominal in diet
Results and discussion
Results: P0 (first parental generation)
Effect levels (P0)
- Dose descriptor:
- NOAEL
- Effect level:
- >= 1 000 ppm (nominal)
- Based on:
- test mat.
- Sex:
- male/female
- Remarks on result:
- other: Generation: all generations (migrated information)
Overall reproductive toxicity
- Reproductive effects observed:
- not specified
Applicant's summary and conclusion
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