Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Additional information:

Diethyleneglycol, propoxylated showed no sensitizing potential in the modified Local Lymph Node Assay (IMDS) in female NMRI mice after dermal application of up to and including a 50 % concentration. Additionally, no indication for a non-specific (irritant) activation was detected. Therefore, the concentration of 50 % turned out to be the NOEL for the parameters investigated in this study with respect to skin sensitization.


Migrated from Short description of key information:
Non sensitiser in a modified Local Lymph Node Assay.

Justification for classification or non-classification

The LLNA result indicates that the substance does not meet the criterion for classification as a skin sensitiser.